BDBM50580007 CHEMBL5072941::US20230357269, Example 15

SMILES O=C1NCCCOc2ccc3[nH]nc(c3c2)-c2cc(cc(N3CCN(C4COC4)CC3)c2)CO1

InChI Key InChIKey=HRFIPUKXVHQUTE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50580007   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Les Laboratoires Servier

US Patent
LigandChemical structure of BindingDB Monomer ID 50580007BDBM50580007(CHEMBL5072941 | US20230357269, Example 15)
Affinity DataIC50: 10nMAssay Description:LRRK2 Kinase reactions were carried out in 384-well white polystyrene plates in a final volume of 6 μl using ADP-Glo Kinase Assay kit (Promega C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2024
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Les Laboratoires Servier

US Patent
LigandChemical structure of BindingDB Monomer ID 50580007BDBM50580007(CHEMBL5072941 | US20230357269, Example 15)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human LRRK2 using LRRKtide peptide and ATP as substrates incubated for 1 hrs by ADP-glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed