BDBM50580032 CHEMBL5078847

SMILES F\C(CNC(=O)NS(=O)(=O)c1cc(Cl)c(Cl)s1)=C1\CCCc2cnn(Cc3ccc(Cl)cc3Cl)c12

InChI Key InChIKey=CBVZXYPCVKQUFI-VKAVYKQESA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50580032   

TargetProstaglandin E2 receptor EP3 subtype(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50580032(CHEMBL5078847)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]-PGE2 from human EP3 receptor assessed as inhibition constant incubated for 2 hrs by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50580032(CHEMBL5078847)
Affinity DataIC50:  1nMAssay Description:Antagonist activity at human EP3 receptor expressed in CHO-K1 cells assessed as reduction in sulprostone induced inhibition of forskolin stimulated c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed