BDBM50580100 CHEMBL5089227

SMILES Cc1cn([C@H]2C[C@H]([C@@H](CO)O2)n2cc(COc3ccc4oc(=O)ccc4c3)nn2)c(=O)[nH]c1=O

InChI Key InChIKey=CZGFBOOZLDNOSG-UHFFFAOYSA-N

Data  7 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50580100   

TargetCarbonic anhydrase 12(Human)
Institute of Biomedical Chemistry

Curated by ChEMBL
LigandPNGBDBM50580100(CHEMBL5089227)
Affinity DataKi:  3.60nMAssay Description:Inhibition of human carbonic anhydrase 12 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Institute of Biomedical Chemistry

Curated by ChEMBL
LigandPNGBDBM50580100(CHEMBL5089227)
Affinity DataKi:  9.30nMAssay Description:Inhibition of human carbonic anhydrase 7 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Human)
Institute of Biomedical Chemistry

Curated by ChEMBL
LigandPNGBDBM50580100(CHEMBL5089227)
Affinity DataKi:  58nMAssay Description:Inhibition of human carbonic anhydrase 5A by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetCarbonic anhydrase 5B, mitochondrial(Human)
Institute of Biomedical Chemistry

Curated by ChEMBL
LigandPNGBDBM50580100(CHEMBL5089227)
Affinity DataKi:  161nMAssay Description:Inhibition of human carbonic anhydrase 5B by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institute of Biomedical Chemistry

Curated by ChEMBL
LigandPNGBDBM50580100(CHEMBL5089227)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of telomerase in human HCT-116 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Institute of Biomedical Chemistry

Curated by ChEMBL
LigandPNGBDBM50580100(CHEMBL5089227)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Institute of Biomedical Chemistry

Curated by ChEMBL
LigandPNGBDBM50580100(CHEMBL5089227)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human carbonic anhydrase 1 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institute of Biomedical Chemistry

Curated by ChEMBL
LigandPNGBDBM50580100(CHEMBL5089227)
Affinity DataIC50: 1.48E+4nMAssay Description:Inhibition of telomerase in human COLO 205 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institute of Biomedical Chemistry

Curated by ChEMBL
LigandPNGBDBM50580100(CHEMBL5089227)
Affinity DataIC50: 2.86E+4nMAssay Description:Inhibition of telomerase in human HT-29 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institute of Biomedical Chemistry

Curated by ChEMBL
LigandPNGBDBM50580100(CHEMBL5089227)
Affinity DataIC50: 3.24E+4nMAssay Description:Inhibition of telomerase in human SW-620 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Institute of Biomedical Chemistry

Curated by ChEMBL
LigandPNGBDBM50580100(CHEMBL5089227)
Affinity DataKi:  6.54E+4nMAssay Description:Inhibition of human carbonic anhydrase 9 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed