BDBM50580159 CHEMBL5094282

SMILES CS(=O)(=O)CCN(Cc1ccc(o1)-c1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1)C(=O)CCC(=O)OCCN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc23)CC1

InChI Key InChIKey=OVNXJZUYPUTQOA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50580159   

TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50580159(CHEMBL5094282)
Affinity DataIC50: 11nMAssay Description:Inhibition of exogenous EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetAldehyde dehydrogenase 1A1(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50580159(CHEMBL5094282)
Affinity DataIC50: 86nMAssay Description:Inhibition of ALDH1A1 in human drug-tolerant MDA-MB-231/lapatinib cells assessed as after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed