BDBM50580331 CHEMBL5083517
SMILES CC(C)C[C@@H]1NC(=O)[C@H](CCCCNC(=O)CC[C@H](NC1=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)c1nc2ccccc2s1)NC(C)=O
InChI Key InChIKey=LOJOAZJDEFCKLF-ZJZGAYNASA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50580331
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of recombinant thrombin (unknown origin) using D-Phe-Pip-Arg-pNA as substrate preincubated for 30 mins followed by substrate addition by c...More data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Human)
Washington University School of Medicine
Curated by ChEMBL
Washington University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 4.47E+3nMAssay Description:Inhibition of recombinant human HGFA serine protease domain using Boc-QLR-AMC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
Affinity DataIC50: 723nMAssay Description:Inhibition of recombinant C-terminal 10His-tagged human coagulation factor 10a (Leu24 to Lys488 residues) expressed in baculovirus infected Sf9 insec...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of recombinant human C-terminal 10-His tagged hepsin (Arg45 to Leu417) expressed in mouse myeloma cells using Boc-QAR-AMC as substrate pre...More data for this Ligand-Target Pair
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine
Curated by ChEMBL
Washington University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair