BDBM50580358 CHEMBL5082014

SMILES Clc1cnc(COc2cc3c(cc(cc3cn2)C(=O)N2CCC(CC2)(C#N)c2ccccn2)C(=O)N2CCCCC2)c(Cl)c1

InChI Key InChIKey=ZBGIBZWECLXNQG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50580358   

TargetCoagulation factor XI(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50580358(CHEMBL5082014)
Affinity DataEC50:  4.30nMAssay Description:Inhibition of human coagulation factor 11 assessed as inhibition of factor 12a mediated activation using z-GPR-AFC measured after 60 mins by fluoresc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed