BDBM50580422 CHEMBL5076784

SMILES Cn1c(NCCNc2c3CCCCc3nc3ccc(Cl)cc23)nc(cc1=O)-c1ccncc1F

InChI Key InChIKey=XAXUQOOLGPCCJX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50580422   

TargetGlycogen synthase kinase-3 beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580422(CHEMBL5076784)
Affinity DataIC50: 8.13E+3nMAssay Description:Inhibition of human recombinant GSK-3beta using prephosphorylated polypeptide as substrate incubated for 30 mins in presence of ATP by Kinase-Glo lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetAcetylcholinesterase(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580422(CHEMBL5076784)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of mouse AChE using acetylthiocholine iodide as substrate incubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed