BDBM50580597 CHEMBL5075228

SMILES Nc1ncnc2n(CCCCCN3CCN(CC3)C(=O)C=C)nc(-c3ccc(F)cc3)c12

InChI Key InChIKey=GOOHQQKXWCOUPK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50580597   

TargetFibroblast growth factor receptor 1(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50580597(CHEMBL5075228)
Affinity DataIC50: 185nMAssay Description:Inhibition of human FGFR1 (459 to 765 residues) expressed in Escherichia coli BL21 (DE3) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50580597(CHEMBL5075228)
Affinity DataIC50: 321nMAssay Description:Inhibition of human FGFR3 (450 to 758 residues) expressed in Escherichia coli BL21 (DE3) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50580597(CHEMBL5075228)
Affinity DataIC50: 337nMAssay Description:Inhibition of human FGFR2 (458 to 768 residues) expressed in Escherichia coli BL21 (DE3) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 4(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50580597(CHEMBL5075228)
Affinity DataIC50: 2.99E+3nMAssay Description:Inhibition of human FGFR4 (445 to 753 residues) expressed in Escherichia coli BL21 (DE3) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed