BDBM50580633 CHEMBL5090952::US20240150297, Compound 18d

SMILES Cc1n[nH]c(C)c1N1CCN(CC1)c1cc(ccc1C)C(O)=O

InChI Key InChIKey=FSSNALBCZQRFIJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50580633   

TargetTransthyretin(Human)
Albany College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50580633(CHEMBL5090952 | US20240150297, Compound 18d)
Affinity DataIC50:  210nMAssay Description:Binding affinity to human plasma TTR tetramer assessed as displacement of diclofenac-coupled FITC by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetAT-rich interactive domain-containing protein 4A(Human)
Columbia University

US Patent
LigandPNGBDBM50580633(CHEMBL5090952 | US20240150297, Compound 18d)
Affinity DataIC50: >3.00E+3nMAssay Description:In vitro binding of compounds to RBP4. Compound binding to RBP4 was assessed in the radiometric scintillation proximity (SPA) assay that was previous...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTransthyretin(Human)
Albany College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50580633(CHEMBL5090952 | US20240150297, Compound 18d)
Affinity DataIC50:  210nMAssay Description:Compound binding to TTR was assessed in the fluorescence polarization assay. The assay measured competitive displacement of the fluorescent probe, FI...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRetinol-binding protein 4(Human)
Albany College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50580633(CHEMBL5090952 | US20240150297, Compound 18d)
Affinity DataIC50: >3.00E+3nMAssay Description:Displacement of [3H]-all trans retinol from human urine biotinylated RBP4 incubated for 16 hrs measured by Scintillation Proximity AssayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed