BDBM50581228 CHEMBL5081341

SMILES COc1nc(C)nc2[nH]cc(-c3ccnc(N)c3)c12

InChI Key InChIKey=MOYYMSNZEWQWQJ-UHFFFAOYSA-N

Data  1 KI  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50581228   

LigandPNGBDBM50581228(CHEMBL5081341)
Affinity DataKi:  10nMAssay Description:Binding affinity to DYRK1A (unknown origin) assessed as inhibition constant by ADP hunter plus assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

LigandPNGBDBM50581228(CHEMBL5081341)
Affinity DataIC50:  18nMAssay Description:Inhibition of DYRK1A (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

LigandPNGBDBM50581228(CHEMBL5081341)
Affinity DataIC50:  22nMAssay Description:Inhibition of DYRK1B (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

LigandPNGBDBM50581228(CHEMBL5081341)
Affinity DataIC50:  65nMAssay Description:Inhibition of DYRK2 (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCyclin-dependent kinase 9(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50581228(CHEMBL5081341)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of CDK9 (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase PAK 4(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50581228(CHEMBL5081341)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of PAK4 (unknown origin) by ADP hunter plus assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase pim-1(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50581228(CHEMBL5081341)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of PIM1 (unknown origin) by ADP hunter plus assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetAurora kinase A(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50581228(CHEMBL5081341)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Aurora A (unknown origin) by ADP hunter plus assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

LigandPNGBDBM50581228(CHEMBL5081341)
Affinity DataIC50:  20nMAssay Description:Inhibition of DYRK1A (unknown origin) assessed as accumulation of ADP by ADP hunter plus assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

LigandPNGBDBM50581228(CHEMBL5081341)
Affinity DataIC50:  60nMAssay Description:Inhibition of DYRK2 (unknown origin) by ADP hunter plus assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed