BDBM50581234 CHEMBL5090159

SMILES Cc1cc(COc2nc(C)nc3[nH]cc(-c4ccnc(N)c4)c23)no1

InChI Key InChIKey=CIJWGWNHXQYIJC-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50581234   

LigandPNGBDBM50581234(CHEMBL5090159)
Affinity DataIC50: 11nMAssay Description:Inhibition of DYRK1A (unknown origin) assessed as accumulation of ADP by ADP hunter plus assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
LigandPNGBDBM50581234(CHEMBL5090159)
Affinity DataIC50: 15nMAssay Description:Inhibition of DYRK1A (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
LigandPNGBDBM50581234(CHEMBL5090159)
Affinity DataIC50: 18nMAssay Description:Inhibition of DYRK1B (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50581234(CHEMBL5090159)
Affinity DataIC50: 33nMAssay Description:Inhibition of CLK (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50581234(CHEMBL5090159)
Affinity DataIC50: 100nMAssay Description:Inhibition of TTK (unknown origin) by ADP hunter plus assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
LigandPNGBDBM50581234(CHEMBL5090159)
Affinity DataIC50: 400nMAssay Description:Inhibition of DYRK2 (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50581234(CHEMBL5090159)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK9 (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50581234(CHEMBL5090159)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of PIM1 (unknown origin) by ADP hunter plus assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed