BDBM50581290 CHEMBL5093179

SMILES CCN(CC)CCNC(=O)c1ccc(NC(=O)CCCCCCC(=O)NO)cc1

InChI Key InChIKey=QQUIELKEKZKGMG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50581290   

TargetHistone deacetylase 6(Human)
Cnrs Erl 9195

Curated by ChEMBL
LigandPNGBDBM50581290(CHEMBL5093179)
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant HDAC6 using Tosyl-Gly-ProLys(Ac)-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Cnrs Erl 9195

Curated by ChEMBL
LigandPNGBDBM50581290(CHEMBL5093179)
Affinity DataIC50: 60nMAssay Description:Inhibition of human HDAC using human HeLa cell nuclear extract measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Cnrs Erl 9195

Curated by ChEMBL
LigandPNGBDBM50581290(CHEMBL5093179)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant HDAC1 using Tosyl-Gly-ProLys(Ac)-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Cnrs Erl 9195

Curated by ChEMBL
LigandPNGBDBM50581290(CHEMBL5093179)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant HDAC3 using Tosyl-Gly-ProLys(Ac)-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Cnrs Erl 9195

Curated by ChEMBL
LigandPNGBDBM50581290(CHEMBL5093179)
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant HDAC2 using Tosyl-Gly-ProLys(Ac)-AMC as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed