BDBM50581498 CHEMBL5079619

SMILES CCC(=O)N(CC(C)N1CCC(Cc2ccccc2)CC1)c1ccc(F)cc1

InChI Key InChIKey=AKMGINAGUXDWSI-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50581498   

TargetMu-type opioid receptor(Rat)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50581498(CHEMBL5079619)
Affinity DataKi:  4.40nMAssay Description:Displacement of [3H]DAMGO from MOR in Sprague-Dawley rat brain membranes measured after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50581498(CHEMBL5079619)
Affinity DataKi:  5.5nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain membranes incubated for 90 mins by liquid scintillation counting metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50581498(CHEMBL5079619)
Affinity DataEC50:  6.10nMAssay Description:Agonist activity at human MOR expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP accumulation incubated for 60 mins by cAM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed