BDBM50581564 CHEMBL5092963

SMILES c1ccc([C@H]2CN(c3cc(O[C@H]4C[C@@H](n5cccn5)C4)ncn3)CCO2)cc1

InChI Key InChIKey=JXGFJBHPOCYADP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50581564   

TargetElongation of very long chain fatty acids protein 1(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581564BDBM50581564(CHEMBL5092963)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of ELOVL1 in HEK293 cells assessed as reduction of C26:0 lipo phosphatidyl choline synthesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581564BDBM50581564(CHEMBL5092963)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetElongation of very long chain fatty acids protein 6(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581564BDBM50581564(CHEMBL5092963)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of ELOVL6 in HEK293 cells by radiometric enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed