BDBM50581647 CHEMBL5094288

SMILES COc1cc(ccc1Nc1ncc2c(C)cc(=O)n(-c3cccc(NC(=O)C=C)c3)c2n1)N1CCN(CC#C)CC1

InChI Key InChIKey=WNKWRNSHNFLXFT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50581647   

TargetEpidermal growth factor receptor(Human)
University of Macau

Curated by ChEMBL
LigandPNGBDBM50581647(CHEMBL5094288)
Affinity DataIC50: 8nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) using Poly (Glu, Tyr)4:1 as substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed