BDBM50582085 CHEMBL5092574

SMILES O=c1ccc2c([nH]1)CCC(NCCCCCCCCCNc1c3c(nc4cc(Cl)ccc14)CCCC3)C2

InChI Key InChIKey=VYHFAHCHRHNJPA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50582085   

TargetAcetylcholinesterase(Rat)
The Hong Kong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582085BDBM50582085(CHEMBL5092574)
Affinity DataIC50: 29nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
The Hong Kong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582085BDBM50582085(CHEMBL5092574)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of rat serum BChE using butyrylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Hong Kong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582085BDBM50582085(CHEMBL5092574)
Affinity DataIC50: 2.76E+3nMAssay Description:Inhibition of hERG expressed in CHO-K1 cells assessed as reduction in thallium influx incubated for 30 minutes by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed