BDBM50582102 CHEMBL5085211

SMILES COc1cc2cc(ccc2c(OC)c1Oc1cc(nc(Nc2ccc(cc2)C#N)n1)N1CCC(O)C1)C#N

InChI Key InChIKey=YLZNKJOFTVOTNJ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50582102   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yanbian University College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50582102(CHEMBL5085211)
Affinity DataIC50: 100nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorimetric anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Yanbian University College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50582102(CHEMBL5085211)
Affinity DataIC50: 150nMAssay Description:Inhibition of HIV1 reverse transcriptase E138K mutant using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorimetric a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Yanbian University College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50582102(CHEMBL5085211)
Affinity DataIC50: 180nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorimetric a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Yanbian University College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50582102(CHEMBL5085211)
Affinity DataIC50: 240nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorimetric a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Yanbian University College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50582102(CHEMBL5085211)
Affinity DataIC50: 450nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Yanbian University College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50582102(CHEMBL5085211)
Affinity DataIC50: 490nMAssay Description:Inhibition of HIV1 reverse transcriptase L100I mutant using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorimetric a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Yanbian University College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50582102(CHEMBL5085211)
Affinity DataIC50: 880nMAssay Description:Inhibition of HIV1 reverse transcriptase F227L/V106A double mutant using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrof...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Yanbian University College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50582102(CHEMBL5085211)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of HIV1 reverse transcriptase Y188L mutant using oligo(dT)16 as primer measured after 40 mins by picogreen-dye based spectrofluorimetric a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed