BDBM50582243 CHEMBL5081174

SMILES CN1CCN(CC1)C1CCN(CC1)c1cc(Cl)c(Nc2ncc(Cl)c(Nc3ccccc3P(C)(C)=O)n2)cc1Cl

InChI Key InChIKey=NGCUFPTULYPMMY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50582243   

TargetEpidermal growth factor receptor(Human)
R. C. Patel Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582243BDBM50582243(CHEMBL5081174)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
R. C. Patel Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582243BDBM50582243(CHEMBL5081174)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) measured by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
R. C. Patel Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50582243BDBM50582243(CHEMBL5081174)
Affinity DataIC50: 66nMAssay Description:Inhibition of wild type EGFR (unknown origin) measured by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed