BDBM50582299 CHEMBL5091051

SMILES O=C(NCCN1CCCCC1)c1cccn2c1nc1c3ccccc3ccc1c2=O

InChI Key InChIKey=BACAFWUTNOGATK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50582299   

TargetDNA-directed RNA polymerase I subunit RPA1(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50582299(CHEMBL5091051)
Affinity DataIC50: 640nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50582299(CHEMBL5091051)
Affinity DataIC50: 3.72E+3nMAssay Description:Inhibition on hERG expressed in HEK293 cells by Qpatch methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50582299(CHEMBL5091051)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human hepatic CYP1A2 expressed in baculovirus insect cell expression system in presence of CEC substrate measured by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed