BDBM50582860 CHEMBL5078455

SMILES OC(=O)[C@@H]1CCCCN1Cc1ccc(OCc2cccc(c2Br)-c2ccccc2)c(Br)c1

InChI Key InChIKey=AHFXYBDSOWECNI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50582860   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50582860(CHEMBL5078455)
Affinity DataIC50: 15nMAssay Description:Inhibition of human PD-1/PD-L1 interaction incubated for 2 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50582860(CHEMBL5078455)
Affinity DataIC50: 15nMAssay Description:Inhibition of PD-1/PDL-1 (unknown origin) bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50582860(CHEMBL5078455)
Affinity DataEC50:  6.60E+3nMAssay Description:Inhibition of PD-1/PD-L1 interaction in human Jurkat T cells co-cultured with CHO/TCRAct/PDL1 cells assessed as restoration of T cell activation meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed