BDBM50582886 CHEMBL5085724

SMILES Cc1cccnc1C(NC(=O)c1cc2cccc(C)c2[nH]1)C1CC1

InChI Key InChIKey=QXMZPTHMVZPHBT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50582886   

TargetHistone-lysine N-methyltransferase SETD2(Human)
Epizyme

Curated by ChEMBL
LigandPNGBDBM50582886(CHEMBL5085724)
Affinity DataIC50: 2.08E+3nMAssay Description:Inhibition of SETD2 (unknown origin) preincubated for 30 mins followed by SAM substrate addition measured after 2 hrs by plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase NSD2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50582886(CHEMBL5085724)
Affinity DataIC50: 3.08E+3nMAssay Description:Inhibition of MMSET (953 to 1240 residues) (unknown origin) by Alpha Screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed