BDBM50583168 CHEMBL5077271

SMILES CC(C)N1CCN(CC1)C(=O)c1ccc(Nc2ncc(F)c(n2)-c2ccc3ncc(nc3c2)N(C)C)nc1

InChI Key InChIKey=DEIFYFMWJVRUHV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50583168   

TargetCyclin-dependent kinase 6(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50583168(CHEMBL5077271)
Affinity DataIC50: 118nMAssay Description:Inhibition of CDK6 (unknown origin) by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50583168(CHEMBL5077271)
Affinity DataIC50: 858nMAssay Description:Inhibition of PIM1 (unknown origin) using 5FAM-ARKRRRHPSGPPTA peptide substrate incubated for 2 hrs by by electrophoretic mobility change analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed