BDBM50583917 CHEMBL4800180
SMILES CCc1cnc(N[C@H]2CCCNC2)nc1-c1c[nH]c2ccccc12
InChI Key InChIKey=HZZNUWNFLHMBRW-AWEZNQCLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50583917
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Syros Pharmaceuticals
Curated by ChEMBL
Syros Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 923nMAssay Description:Inhibition of CDK2/cyclin E1 (unknown origin) using 5-FAM-labeled peptide as substrate in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 135nMAssay Description:Inhibition of CDK12/cyclin K (unknown origin) using 5-FAM-labeled peptide as substrate in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 430nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin) using 5-FAM-labeled peptide as substrate in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.400nMAssay Description:Binding affinity to full length CDK7 (1 to 346 residues) /N-terminal TEV cleavable 6His tagged full length cyclinH (1 to 323 residues) (unknown origi...More data for this Ligand-Target Pair