BDBM50583931 CHEMBL5086077
SMILES CC(C)OC1CN(C1)C(=O)NCc1ccc(cc1Cl)-c1ccnc(Nc2cnn(C)c2)n1
InChI Key InChIKey=CGCUIKPUGNWBHF-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50583931
Affinity DataIC50: 520nMAssay Description:Inhibition of BTK phosphorylation in human whole blood assessed as reduction in BTK phosphorylation incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair