BDBM50583998 CHEMBL5074219

SMILES COCCOCCOc1cc2[nH]c(CNc3nc(nc4n(cnc34)C(C)C)N3CCOCC3)nc2cc1F

InChI Key InChIKey=KHWWVAVHHRPPQY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50583998   

TargetCyclin-dependent kinase 12(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50583998(CHEMBL5074219)
Affinity DataIC50: 237nMAssay Description:Inhibition of human CDK12 (696 to 1082 residues) /cyclinK (1 to 300 residues) using ac-YSPTSPpSYSPTSFpS-YSPTSPpSY-[PEG2]-RR-amid peptide as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed