BDBM50584266 CHEMBL5087043

SMILES Cc1c(CN2CCN(CC2)C(=O)C2CCCC2)cccc1Nc1nc2CCCCc2s1

InChI Key InChIKey=IMIUNFJBYQQBMM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50584266   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50584266(CHEMBL5087043)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of human recombinant DHODH expressed in Escherichia coli BL21 (DE3) using dihydroorotate as substrate and CoQ6 as co-substrate incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50584266(CHEMBL5087043)
Affinity DataIC50: 1.67E+3nMAssay Description:Inhibition of human GAL4-fused RORgammat LBD transfected in HEK293T cell measured after 24 hrs by by dual-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed