BDBM50584275 CHEMBL5082516

SMILES COC1CCCc2sc(Nc3cccc(CN4CCN(CC4)C(=O)C4CCCC4)c3C)nc12

InChI Key InChIKey=IBHPNMQFVCWSCE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50584275   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50584275(CHEMBL5082516)
Affinity DataIC50:  9.32E+3nMAssay Description:Inhibition of human recombinant DHODH expressed in Escherichia coli BL21 (DE3) using dihydroorotate as substrate and CoQ6 as co-substrate incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50584275(CHEMBL5082516)
Affinity DataIC50:  789nMAssay Description:Inhibition of human GAL4-fused RORgammat LBD transfected in HEK293T cell measured after 24 hrs by by dual-glo luciferase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed