BDBM50584320 CHEMBL5073571

SMILES CC(C)(Cn1c(c(cn1)Nc2ncc3cc(c(cc3n2)C4CCN(CC4)C5COC5)Cl)Cl)O

InChI Key InChIKey=MYRFCAOJVUFSNI-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50584320   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck

Curated by ChEMBL

LigandBDBM50584320(CHEMBL5073571)Copy SMILESCopy InChI

Affinity DataIC50: 0.800nMAssay Description:Inhibition of recombinant N-terminal GST-fused LRRK2 G2109S mutant (970 to 2527 residues) (unknown origin) preincubated with enzyme for 15 mins follo...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
3/6/2023
Entry Details Article
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck

Curated by ChEMBL

LigandBDBM50584320(CHEMBL5073571)Copy SMILESCopy InChI

Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human ERG by voltage clamp assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
3/6/2023
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL