BDBM50584321 CHEMBL5090739

SMILES Clc1c(Nc2ncc3cc(Cl)c(cc3n2)C2CCN(CC2)C2COC2)cnn1C1CC1

InChI Key InChIKey=OPPFIBBBZVPOMK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50584321   

LigandChemical structure of BindingDB Monomer ID 50584321BDBM50584321(CHEMBL5090739 | US12540131, Ex-8.8)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant N-terminal GST-fused LRRK2 G2109S mutant (970 to 2527 residues) (unknown origin) preincubated with enzyme for 15 mins follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50584321BDBM50584321(CHEMBL5090739 | US12540131, Ex-8.8)
Affinity DataIC50: 0.631nMAssay Description:HEK cells transfected with the human mGluR5a receptor (H10H cell line) were plated at 15,000 cells/well in clear-bottomed poly-D-lysine-coated assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 50584321BDBM50584321(CHEMBL5090739 | US12540131, Ex-8.8)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human ERG by voltage clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed