BDBM50584322 CHEMBL5089102

SMILES Cc1c(Nc2ncc3cc(Cl)c(cc3n2)C2CCN(CC2)C2COC2)cnn1C1CC1

InChI Key InChIKey=IAONRTHJRPJWJO-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50584322   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck

Curated by ChEMBL

LigandBDBM50584322(CHEMBL5089102)Copy SMILESCopy InChI

Affinity DataIC50: 0.650nMAssay Description:Inhibition of recombinant N-terminal GST-fused LRRK2 G2109S mutant (970 to 2527 residues) (unknown origin) preincubated with enzyme for 15 mins follo...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/6/2023
Entry Details Article
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck

Curated by ChEMBL

LigandBDBM50584322(CHEMBL5089102)Copy SMILESCopy InChI

Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human ERG by voltage clamp assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/6/2023
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL