BDBM50584413 CHEMBL5084290

SMILES CC(C)c1ccc(C)c(Oc2nccc(n2)-c2c(ncn2C2CCNCC2)-c2ccc(cc2)C(F)(F)F)c1

InChI Key InChIKey=ULDFEUPLPPWJDA-UHFFFAOYSA-N

Data  1 KI  9 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50584413   

TargetBromodomain-containing protein 4(Human)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50584413BDBM50584413(CHEMBL5084290)
Affinity DataIC50: 12nMAssay Description:Inhibition of His9-tagged BRD4-BD1 (unknown origin) using Ac-SGRGK(Ac)GGK(Ac)GLGK(Ac)GGAK(Ac)RHRKVLR-Peg-(Biot) as substrate incubated for 1 hr and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50584413BDBM50584413(CHEMBL5084290)
Affinity DataIC50: 59nMAssay Description:Inhibition of his9-tagged BRD4-BD1 (unknown origin) preincubated for 30 mins followed by addition of biotinylated peptide and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBromodomain-containing protein 2(Human)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50584413BDBM50584413(CHEMBL5084290)
Affinity DataIC50: 280nMAssay Description:Inhibition of BRD2-BD1 (unknown origin) measured by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50584413BDBM50584413(CHEMBL5084290)
Affinity DataIC50: 300nMAssay Description:Inhibition of BRD4 D1 (unknown origin) by competitive fluorescence anisotropy assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50584413BDBM50584413(CHEMBL5084290)
Affinity DataKi:  503nMAssay Description:Binding affinity to N-luc fused BRD4-BD1 in HEK293T cells assessed as apparent inhibition constant using NanoGlo substrate as substrate incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBromodomain-containing protein 3(Human)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50584413BDBM50584413(CHEMBL5084290)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of BRD3-BD1 (unknown origin) measured by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50584413BDBM50584413(CHEMBL5084290)
Affinity DataEC50:  1.31E+3nMAssay Description:Inhibition of N-luc fused BRD4-BD1 in HEK293T cells using NanoGlo substrate as substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBromodomain-containing protein 2(Human)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50584413BDBM50584413(CHEMBL5084290)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of BRD2-BD2 (unknown origin) measured by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50584413BDBM50584413(CHEMBL5084290)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human his tagged BRD4-BD2 using Histone H4 peptide (1-21) K5/8/12/16Ac as substrate preincubated for 30 mins followed by addition of bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50584413BDBM50584413(CHEMBL5084290)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of BRD4-BD2 (unknown origin) measured by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetBromodomain-containing protein 3(Human)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50584413BDBM50584413(CHEMBL5084290)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of BRD3-BD2 (unknown origin) measured by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed