BDBM50584762 CHEMBL5069689

SMILES COc1ccc(Nc2ncc3nc(-c4ccccc4)c(=O)n(-c4cccc(NC(=O)C=C)c4)c3n2)cc1

InChI Key InChIKey=MUHMCFYZMSUSBK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50584762   

TargetTyrosine-protein kinase BTK(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50584762(CHEMBL5069689)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human BTK using poly-Glu-Tyr (4:1) as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50584762(CHEMBL5069689)
Affinity DataIC50: 18nMAssay Description:Inhibition of GST-tagged human EGFR (668 to 1210 residues) expressed in baculovirus expression system using poly-Glu-Tyr (4:1) as substrate incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50584762(CHEMBL5069689)
Affinity DataIC50: 112nMAssay Description:Inhibition of human ITK using poly-Glu-Tyr (4:1) as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed