BDBM50584880 CHEMBL5088178
SMILES OC(=O)c1cccc2c(Cl)c(CNC(=O)c3cnn4cccnc34)oc12
InChI Key InChIKey=HHTSIWUTEYRKSI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50584880
TargetStimulator of interferon genes protein(Human)
Bristol Myers Squibb Research and Development
Curated by ChEMBL
Bristol Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 5.80E+4nMAssay Description:Displacement of fluorescein-labelled probe from wild type human His-tagged STING cytoplasmic domain (155 to 341 residues) by time-resolved FRET-based...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Mouse)
Bristol Myers Squibb Research and Development
Curated by ChEMBL
Bristol Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.90E+4nMAssay Description:Displacement of fluorescein-labelled probe from wild type mouse His-tagged STING cytoplasmic domain (155 to 341 residues) by time-resolved FRET-based...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Mouse)
Bristol Myers Squibb Research and Development
Curated by ChEMBL
Bristol Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataEC50: 6.50E+4nMAssay Description:Binding affinity to wild type mouse His-tagged STING cytoplasmic domain (155 to 341 residues) assessed as induction of protein dimerization incubated...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Bristol Myers Squibb Research and Development
Curated by ChEMBL
Bristol Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Binding affinity to wild type human His-tagged STING cytoplasmic domain (155 to 341 residues) assessed as induction of protein dimerization incubated...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Bristol Myers Squibb Research and Development
Curated by ChEMBL
Bristol Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataEC50: 8.30E+4nMAssay Description:Binding affinity to human STING G230A/R293Q double mutant cytoplasmic domain (155 to 341 residues) assessed as induction of protein dimerization incu...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Bristol Myers Squibb Research and Development
Curated by ChEMBL
Bristol Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 2.40E+4nMAssay Description:Displacement of fluorescein-labelled probe from human cytoplasmic domain of STING G230A/R293Q double mutant (155 to 341 residues) by time-resolved FR...More data for this Ligand-Target Pair