BDBM50584883 CHEMBL5074765

SMILES [H][C@]12C[C@@H](c3ccc(cc3)-c3cc(cc4cc(ccc34)-c3ccc(cc3)C(F)(F)F)C(O)=O)[C@]([H])(CN1)C2

InChI Key InChIKey=PXJXLYRJAGOTQU-RMDSEJHCSA-N

Data  9 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50584883   

TargetD(1B) dopamine receptor(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50584883(CHEMBL5074765)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of dopamine D5 receptor (unknown origin) assessed as binding constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50584883(CHEMBL5074765)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of dopamine D3 receptor (unknown origin) assessed as binding constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50584883(CHEMBL5074765)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of adrenergic beta 3 receptor (unknown origin) assessed as binding constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50584883(CHEMBL5074765)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of serotonin 5HT1D receptor (unknown origin) assessed as binding constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50584883(CHEMBL5074765)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of adrenergic alpha 2B receptor (unknown origin) assessed as binding constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50584883(CHEMBL5074765)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of sigma 2 receptor (unknown origin) assessed as binding constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50584883(CHEMBL5074765)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of dopamine D1 receptor (unknown origin) assessed as binding constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranslocator protein(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50584883(CHEMBL5074765)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of TSPO receptor (unknown origin) assessed as binding constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50584883(CHEMBL5074765)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition of sigma 1 receptor (unknown origin) assessed as binding constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50584883(CHEMBL5074765)
Affinity DataIC50:  8.60nMAssay Description:Inhibition of fluorescent antagonist binding to human P2Y14R expressed in CHO cells preincubated for 30 mins followed by 6-amino-9-(2-carboxy-4-((6-(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 14(Mus musculus)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50584883(CHEMBL5074765)
Affinity DataIC50:  13nMAssay Description:Inhibition of fluorescent antagonist binding to mouse P2Y14R expressed in HEK293 cells preincubated for 30 mins followed by addition of 6-amino-9-(2-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed