BDBM50584992 CHEMBL5085734

SMILES CC(C)c1ccccc1-c1nc(NCc2ccccn2)c2n(C)ccc2n1

InChI Key InChIKey=XIEZMAUGHWKZDR-UHFFFAOYSA-N

Data  4 IC50  2 Kd

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50584992   

TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50584992(CHEMBL5085734)
Affinity DataIC50: <2.51E+4nMAssay Description:Inhibition of PI5P4Kbeta (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 alpha(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50584992(CHEMBL5085734)
Affinity DataIC50: <5.01E+4nMAssay Description:Inhibition of PI5P4Kalpha (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 alpha(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50584992(CHEMBL5085734)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PI5P4Kalpha (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50584992(CHEMBL5085734)
Affinity DataKd:  68nMAssay Description:Binding affinity to PI5P4Kgamma (unknown origin) by KINOMEscan analysisMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50584992(CHEMBL5085734)
Affinity DataKd: >3.00E+4nMAssay Description:Binding affinity to PI5P4Kbeta (unknown origin) by KINOMEscan analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50584992(CHEMBL5085734)
Affinity DataIC50:  794nMAssay Description:Binding affinity to ePL-tagged wild type PI5P4Kgamma (unknown origin) expressed in HEK293 cells incubated for 60 mins by InCell pulse thermal stabili...More data for this Ligand-Target Pair