BDBM50585202 CHEMBL5091582

SMILES Cc1nn(CC(F)(F)F)cc1Nc1nccc(NCCc2cnc[nH]2)n1

InChI Key InChIKey=ZJECJFJNVHNEPD-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50585202   

TargetMyosin light chain kinase 2, skeletal/cardiac muscle(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50585202(CHEMBL5091582)
Affinity DataIC50: 479nMAssay Description:Inhibition of full length recombinant human MYLK2 using KKLNRTLSFAEPG as substrate incubated for 40 mins in presence of [gamma-33P-ATP] by radiometri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetMyosin light chain kinase 2, skeletal/cardiac muscle(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50585202(CHEMBL5091582)
Affinity DataIC50: 3.67E+3nMAssay Description:Inhibition of NanoLuc-fused MYLK2 (unknown origin) expressed in HEK293 cells incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetMAP/microtubule affinity-regulating kinase 4(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50585202(CHEMBL5091582)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of tracer K5 from NLuc fused MARK4 (unknown origin) expressed in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase 17A(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50585202(CHEMBL5091582)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of tracer K9 from NLuc fused DRAK1 (unknown origin) expressed in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase TBK1(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50585202(CHEMBL5091582)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of tracer K5 from NLuc fused TBK1 (unknown origin) expressed in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetMAP/microtubule affinity-regulating kinase 3(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50585202(CHEMBL5091582)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of tracer K9 from NLuc fused MARK3 (unknown origin) expressed in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed