BDBM50585422 CHEMBL5085644

SMILES NS(=O)(=O)c1ccc2N(Cc3ccc(cc3)C(F)(F)F)C(=O)C(=O)c2c1

InChI Key InChIKey=AORLMFHIOLHBMN-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50585422   

TargetCarbonic anhydrase 2(Human)
Gause Institute of New Antibiotics

Curated by ChEMBL
LigandPNGBDBM50585422(CHEMBL5085644)
Affinity DataKi:  7.90nMAssay Description:Inhibition of human CA2 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Gause Institute of New Antibiotics

Curated by ChEMBL
LigandPNGBDBM50585422(CHEMBL5085644)
Affinity DataKi:  84nMAssay Description:Inhibition of human CA1 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Gause Institute of New Antibiotics

Curated by ChEMBL
LigandPNGBDBM50585422(CHEMBL5085644)
Affinity DataKi:  86nMAssay Description:Inhibition of human CA12 preincubated for 15 mins by phenol red based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Gause Institute of New Antibiotics

Curated by ChEMBL
LigandPNGBDBM50585422(CHEMBL5085644)
Affinity DataKi:  811nMAssay Description:Inhibition of human CA9 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed