BDBM50585762 CHEMBL5077138

SMILES CN1CCC(CC1)[C@@](C)(O)c1ccc2cnc(Nc3ccc(cc3F)S(C)(=O)=O)cc2n1

InChI Key InChIKey=FONDNEXKEYTNCS-HSZRJFAPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50585762   

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Goldfinc Bio

Curated by ChEMBL
LigandPNGBDBM50585762(CHEMBL5077138)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of full length N-terminal GST tagged human CDK2(1 to 298 residues)/CyclinA2 (1 to 432 residues) expressed in baculovirus expression system...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCyclin-dependent kinase 5 activator 1(Human)
Goldfinc Bio

Curated by ChEMBL
LigandPNGBDBM50585762(CHEMBL5077138)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of full length N-terminal GST fused human CDK5(1 to 292 residues)/ p25 (99 to 307 residues) expressed in baculovirus expression system usi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed