BDBM50585785 CHEMBL5077028
SMILES CN1CCC(CC1)[C@@](C)(O)c1ccc2cnc(Nc3cc(N4CC5CCC(C4)O5)c(cc3F)C#N)cc2n1
InChI Key InChIKey=PHVGAEJTLZFYTO-UQIPPQJZSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50585785
Affinity DataIC50: 0.800nMAssay Description:Inhibition of full length N-terminal GST fused human CDK5(1 to 292 residues)/ p25 (99 to 307 residues) expressed in baculovirus expression system usi...More data for this Ligand-Target Pair
Affinity DataIC50: 166nMAssay Description:Inhibition of full length N-terminal GST tagged human CDK2(1 to 298 residues)/CyclinA2 (1 to 432 residues) expressed in baculovirus expression system...More data for this Ligand-Target Pair
Affinity DataIC50: 127nMAssay Description:Inhibition of full length N-terminal GST fused human CDK9(1 to 372 residues)/ His- tagged CyclinT1 (1 to 726 residues) expressed in baculovirus expre...More data for this Ligand-Target Pair
TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Goldfinc Bio
Curated by ChEMBL
Goldfinc Bio
Curated by ChEMBL
Affinity DataIC50: 94nMAssay Description:Inhibition of full length N-terminal GST fused human CDK7 (1 to 346 residues)/CyclinH (1 to 323 residues)/ MAT1 (1 to 309 residues) expressed in bacu...More data for this Ligand-Target Pair
Affinity DataIC50: 201nMAssay Description:Inhibition of full length N-terminal GST fused human CDK6 (1 to 326 residues)/CyclinD3 (1 to 292 residues) expressed in baculovirus expression system...More data for this Ligand-Target Pair