BDBM50586107 CHEMBL5087486

SMILES O=C(Cc1ccc[nH]1)N[C@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5c4[C@@]2(CCN3CC2CC2)[C@H]1O5

InChI Key InChIKey=JRYPGWXQSMLISM-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50586107   

TargetMu-type opioid receptor(Mouse)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50586107BDBM50586107(CHEMBL5087486)
Affinity DataKi:  0.460nMAssay Description:Displacement of [3H]-naloxone from mouse mu opioid receptor expressed in CHO cell membranes assessed as inhibition constant incubated for 1.5 hrs by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50586107BDBM50586107(CHEMBL5087486)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]-diprenorphine from mouse kappa opioid receptor expressed in CHO cell membranes assessed as inhibition constant incubated for 1.5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50586107BDBM50586107(CHEMBL5087486)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]-diprenorphine from human delta opioid receptor expressed in CHO cell membranes assessed as inhibition constant incubated for 1.5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50586107BDBM50586107(CHEMBL5087486)
Affinity DataEC50:  4.20nMAssay Description:Partial agonist activity at mouse mu opioid receptor expressed in CHO cell membranes incubated for 1.5 hrs by [35S]GTPgammaS binding based liquid sci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed