BDBM50586167 CHEMBL5074786

SMILES CCN(c1cc(Cl)c2c(c1Cl)C(=O)N(Cc1c(OC)cc(C)[nH]c1=O)CCN2C)C1CCOCC1

InChI Key InChIKey=YBPNJVZRYWICPU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50586167   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Tri-Institutional Therapeutics Discovery Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50586167BDBM50586167(CHEMBL5074786)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of EZH2 (unknown origin) using 3H-SAM as substrate incubated for 1 hour by filter binding methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed