BDBM50586628 CHEMBL5091826

SMILES COc1cc(ccc1NC(=O)c1cnn2ccc(N[C@@H]3CCCNC3)nc12)N1CCC(CC1)N1CCOCC1

InChI Key InChIKey=WEPQJDKQHHQJDE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50586628   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50586628(CHEMBL5091826)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of FLT3 (unknown origin) using Poly (Glu,Tyr) 4:1 as substrate incubated for 1 hr in presence of ATP by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50586628(CHEMBL5091826)
Affinity DataIC50: 18nMAssay Description:Inhibition of FLT3-ITD mutant (unknown origin) using Poly (Glu,Tyr) 4:1 as substrate incubated for 1 hr in presence of ATP by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed