BDBM50586632 CHEMBL5075169

SMILES COc1cc(ccc1NC(=O)c1cnn2ccc(nc12)N1CCC[C@@H](N)C1)N1CCN(CC1)S(C)(=O)=O

InChI Key InChIKey=QXNRGWZOIAITOU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50586632   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50586632(CHEMBL5075169)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of FLT3 (unknown origin) using Poly (Glu,Tyr) 4:1 as substrate incubated for 1 hr in presence of ATP by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50586632(CHEMBL5075169)
Affinity DataIC50: 19nMAssay Description:Inhibition of FLT3-ITD mutant (unknown origin) using Poly (Glu,Tyr) 4:1 as substrate incubated for 1 hr in presence of ATP by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed