BDBM50586953 CHEMBL5085618

SMILES CS(=O)(=O)Cc1ccc(CNC(=O)c2ccc3[nH]ccc3c2)c(c1)C(F)(F)F

InChI Key InChIKey=CGJAYXGRULEEQH-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50586953   

TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University

Curated by ChEMBL
LigandPNGBDBM50586953(CHEMBL5085618)
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant human full length sEH assessed as reduction in 6-methoxy-2-naphthaldehyde formation using PHOME as substrate preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University

Curated by ChEMBL
LigandPNGBDBM50586953(CHEMBL5085618)
Affinity DataEC50:  2.19E+3nMAssay Description:Partial agonist activity at GAL4-tagged human PPARgamma LBD expressed in HEK293T cells incubated for 12 to 14 hrs by dual-Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed