BDBM50587105 CHEMBL5082751::US20240043470, Compound 2-04
SMILES CC(=O)N[C@H]1Cc2cccc(Oc3ccc(C[C@H](NC(=O)[C@H](CC(=O)N4CCC[C@@H]4c4ccccc4)NC1=O)C(=O)NCc1ccccc1F)cc3)c2
InChI Key InChIKey=UFUWULBTISUDCM-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50587105
Affinity DataIC50: 9.10E+3nMAssay Description:Experiments to determine IC50 values against β5i and β5c for compounds were carried out in 96-well plates. In brief, 1 μL of compound ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.07E+4nMAssay Description:Experiments to determine IC50 values against β5i and β5c for compounds were carried out in 96-well plates. In brief, 1 μL of compound ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human 20S immunoproteasome beta-5i subunit using Suc-LLVY-AMC as substrate measured over 1.5 to 2 hrs by plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human 20S constitutive proteasome beta-5c subunit using Suc-LLVY-AMC as substrate measured over 1.5 to 2 hrs by plate reader assayMore data for this Ligand-Target Pair