BDBM50587106 CHEMBL5074964::US20240043470, Compound 2-06
SMILES Fc1ccccc1CNC(=O)[C@@H]1Cc2ccc(Oc3cccc(C[C@H](NC(=O)c4ccccc4)C(=O)N[C@@H](CC(=O)N4CCC[C@@H]4c4ccccc4)C(=O)N1)c3)cc2
InChI Key InChIKey=AZJASSLTGVDFGP-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50587106
Affinity DataIC50: 1.93E+4nMAssay Description:Experiments to determine IC50 values against β5i and β5c for compounds were carried out in 96-well plates. In brief, 1 μL of compound ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human 20S constitutive proteasome beta-5c subunit using Suc-LLVY-AMC as substrate measured over 1.5 to 2 hrs by plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human 20S immunoproteasome beta-5i subunit using Suc-LLVY-AMC as substrate measured over 1.5 to 2 hrs by plate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Experiments to determine IC50 values against β5i and β5c for compounds were carried out in 96-well plates. In brief, 1 μL of compound ...More data for this Ligand-Target Pair