BDBM50587443 CHEMBL5079807

SMILES CC[C@@H](C)[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC2=NCN=C2)NC(=O)[C@H](Cc2ccccc2)NC(C)=O)CCCn2nncc2COC[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N2CCC[C@H]2C(C)N2CCC[C@H]2C(N)=O)NC1=O

InChI Key InChIKey=IKQOWLZHFWPKEP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50587443   

TargetGTPase KRas(Human)
Cambridge University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587443BDBM50587443(CHEMBL5079807)
Affinity DataIC50: 8.51E+3nMAssay Description:Inhibition of alexa fluor 647-labeled kinase tracer 314 binding to biotinylated-KRAS G12V mutant (unknown origin) measured after 60 mins by HTRF comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetGTPase KRas(Human)
Cambridge University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587443BDBM50587443(CHEMBL5079807)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of alexa fluor 647-labeled kinase tracer 314 binding to biotinylated-KRAS G12V mutant (unknown origin) measured after 60 mins by HTRF comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed