BDBM50587695 CHEMBL5200182

SMILES COc1ccc2[nH]c3c(C)c(C)ccc3c(=O)c2c1

InChI Key InChIKey=SEVGTQHWWAYAQR-UHFFFAOYSA-N

Data  1 IC50  1 Kd  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50587695   

TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50587695(CHEMBL5200182)
Affinity DataIC50: 1.92E+3nMAssay Description:Agonist activity at human STING incubated for 3 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50587695(CHEMBL5200182)
Affinity DataEC50:  7.45E+3nMAssay Description:Agonist activity at STING in human 293T hSTING-R232 Cells incubated for 48 hrs by QUANTI-blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50587695(CHEMBL5200182)
Affinity DataEC50:  7.45E+3nMAssay Description:Activation of STING pathway in human 293T-hSTING-R232 cells incubated for 48 hrs by QUANTI-Luc assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50587695(CHEMBL5200182)
Affinity DataEC50:  1.02E+4nMAssay Description:Agonist activity at STING in mouse 293T Cells incubated for 48 hrs by QUANTI-blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50587695(CHEMBL5200182)
Affinity DataEC50:  1.02E+4nMAssay Description:Activation of STING pathway in mouse 293T-mSTING cells incubated for 48 hrs by QUANTI-Luc assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50587695(CHEMBL5200182)
Affinity DataKd:  2.64E+4nMAssay Description:Binding affinity to human STING (137 to 379 residues) assessed as dissociation constant by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed