BDBM50587726 CHEMBL3401107

SMILES Cc1ccc(cc1)-c1nc(SCc2cn(CC(=O)NC(=O)Nc3ccccn3)nn2)nc(Nc2cccc(c2)C(F)(F)F)c1C#N

InChI Key InChIKey=YEQNUHCFWUDZRO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50587726   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50587726(CHEMBL3401107)
Affinity DataIC50:  183nMAssay Description:Inhibition of recombinant LSD1 (unknown origin) transfected in Escherichia coli BL21 (DE) using H3Kme2 as a substrate incubated for 30 mins by fluore...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50587726(CHEMBL3401107)
Affinity DataIC50:  183nMAssay Description:Mean functional activity against human H3 receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Beijing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50587726(CHEMBL3401107)
Affinity DataIC50:  183nMAssay Description:Inhibition of full-length recombinant KDM1A (unknown origin) expressed in Escherichia coli BL21 DE using H3K4Me2 peptide as substrate incubated for 0...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed