BDBM50587727 CHEMBL5204926

SMILES N[C@@H]1COCC11CCN(CC1)c1cnc2c(Sc3cccc(Cl)c3Cl)n[nH]c2n1

InChI Key InChIKey=KAOHZVCVDBIQAP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50587727   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587727BDBM50587727(CHEMBL5204926)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of N-terminal 6His-tagged full-length H2N-VE(pY)LDLDLD(PEG8)RVD(pY)VVVDQQ-amide-activated SHP2 (247 to 529 residues) (unknown origin) expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587727BDBM50587727(CHEMBL5204926)
Affinity DataIC50: 2.10nMAssay Description:Antagonist activity at full length ERbeta (unknown origin) assessed as reduction in E2 induced response after 24 hrs by cell based ERE-driven lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed